Scientist/Senior Scientist, Antibody Discovery

Waltham, MA
Full Time
Antibody Discovery Services
Mid Level
The Company
We are Alloy Therapeutics—a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.

Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, CH; and Athens, GA and 82VS portfolio companies in Boston, San Francisco, Dallas and Oklahoma City. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture.

This is an on-site and full-time position with flexibility to work from home. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team!

The Team 
Our Alloy Discovery Services (ADS) team is looking for a Scientist/Senior Scientist to join our in-vivo antibody discovery team in Waltham, Massachusetts. The team is responsible for antibody discovery efforts for a wide range of projects using diverse technologies to isolate and sequence antigen-specific B cells from Alloy transgenic mice. Embracing a dynamic, inventive, and teamwork-oriented environment, you'll contribute to our overarching mission with the ultimate goal of helping others to make better medicines.

The Role 
As a Scientist/Senior Scientist, Antibody Discovery, you will work with our ADS team to build new antibody technologies for the discovery of antibody-based therapeutics. You will be responsible for developing, implementing, and using the very latest single-cell techniques with the goal of identifying drug candidates in close collaboration with our partners. You will be a subject-matter expert providing key guidance on overall project strategies, driving efficient execution of lab activities while ensuring high quality deliverables all with a hands-on approach. This role requires an independent sense of urgency and strong organizational skills. 

This role will report to Head of In-Vivo Antibody Discovery with autonomy owning various stakeholders, projects, and tasks in a dynamic start-up environment while keeping up the pace of Alloy. This is you! 

How You’ll Drive Impact 
  • Improve: Drive the development, implementation, and optimization of cutting-edge antibody discovery technologies.
  • Collaborate: With broader team of scientific experts at Alloy to integrate antibody discovery efficiently into projects and engage with external collaborators in discovery of biologics.
  • Deliver: Efficient execution of partner projects balancing quality, timeline, and costs, while ensuring successful delivery on projects.
  • Lead: Lead by example by going the extra mile to ensure we are successful delivering on projects. 
  • Communicate: Communicate effectively with key stakeholders within the organization, fostering productive interactions across teams at different sites.
Why We Value You 
  • You have experience in in vivo antibody discovery platforms
  • You have expertise with single B cell sorting and sort design
  • You have experience with preparation of immune cells for screening on single-cell platforms
  • You are skilled in functional assay development
  • You have experience in immune repertoire sequencing 
  • You have experience in next-generation sequencing: library preparation and sequencing
  • You have knowledge of high throughput cloning of antibodies
  • You have skilled with immunizations and animal handling 
  • You have ELN and LIMS experience
 Desired Multipliers  
  • PhD in Immunology, Molecular Biology, or related discipline with 0-2 years of experience or your master with +5 years of experience
  • Experience in single-cell microfluidics technologies antibody discovery platforms using transgenic animals
  • Ability to work across various US and international time zones 
  • Accommodate occasional travel as needed (<5%) 
Taking Care of Our People
We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you’re single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.
  • Competitive base and equity compensation commensurate with level of experience and independence
  • 401(k) company match
Health & Family
  • Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered
  • Company-paid disability (STD, LTD) and life insurance
  • Paid parental leave
  • Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval)
Unique Perks
  • Unlimited PTO (paid time off) and flexible schedules
  • Annual stipend for continuing education with commitment to your career through individualized professional development plan
  • Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness
Diversity, Equity, and Inclusion
Here at Alloy, we democratize capabilities for discovering and developing therapeutic biologics. So, being diverse and inclusive isn’t just something we strive for, it is who we are, and part of what we do each and every single day. We want to ensure that as an employee, you feel Alloy is a place where, no matter who you are, you feel safe, included, and that you have the opportunity to bring your unique self to work. 

Alloy Therapeutics is an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status.  If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected].  We will make every effort to respond to your request for disability assistance as soon as possible.

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